Decellularization reduces calcification while improving both durability and 1-year functional results of pulmonary homograft valves in juvenile sheep
نویسندگان
چکیده
منابع مشابه
Radiology of homograft aortic valves.
A consecutive series of 93 patients had homograft.aortic valve replacement at Green Lane Hospital over a six-month period. Except for 12 assessed at one or two months, the 85 survivors were examined at three months and the clinical degree of aortic incompetence was recorded. Thirty-four of the patients did not proceed to aortography for reasons unrelated to the state of the homograft valve. Fif...
متن کاملHomograft valves: is degeneration inevitable?
Since the first successful sub-coronary insertion (Ross 1962), the homograft aortic valve has been the favourite amongst many rypes of mechanicai or biological cardiac vaive repiacements ar the National Heart Hospital. Recent srudies on long rerm patient survivai afrer homograft insertion have reveaied excelient results (Bodnar er ai 1979), surpassed oniy by the autotranspianted puimonary valve...
متن کاملChanges in heart size after homograft replacement of aortic, mitral, or both aortic and mitral valves.
j-Ieart size was measured radiographically before and after single or double homograft valve replacement in 69 consecutive patients. Thirty patients had aortic valve replacement, 25 mitral, and 14 both aortic and mitral valve replacement. For aortic valve replacement a fresh unsupported homograft was inserted in the subcoronary position, while for mitral valve replacement afresh semilunar homog...
متن کاملEvaluation of the biological behavior of decellularized pulmonary homografts: an experimental sheep model.
INTRODUCTION The cryopreserved homograft is a good valve substitute due attributes like excellent hemodynamics, low incidence of thromboembolic events, infection resistance and good mid-term durability. However, progressive homograft degeneration and fibrocalcification may occur, particularly in the childhood and young adults. Their antigenicity triggers an immunological reaction that plays an ...
متن کاملChanges in heart size after homograft replacement of aortic , mitral , or both aortic wand mitral valves
j-Ieart size was measured radiographically before and after single or double homograft valve replacement in 69 consecutive patients. Thirty patients had aortic valve replacement, 25 mitral, and 14 both aortic and mitral valve replacement. For aortic valve replacement a fresh unsupported homograft was inserted in the subcoronary position, while for mitral valve replacement afresh semilunar homog...
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ژورنال
عنوان ژورنال: The Journal of Thoracic and Cardiovascular Surgery
سال: 2009
ISSN: 0022-5223
DOI: 10.1016/j.jtcvs.2008.12.009